Extended release: Take 120 mg every 12 hours or 240 mg every 24 hours. Pseudoephedrine and phenylephrine belong to a class of drugs called alpha-adrenergic agonists, which cause the blood vessels to constrict. Kaunitz AM. -Routine use of acetaminophen during pregnancy is not advised.-Phenylephrine is a sympathomimetic used in emergencies to treat hypotension and alleviate eye and ear allergic symptoms.-Phenylephrine could cause constriction in uterine vessels (that are normally maximally dilated during pregnancy), reducing uterine blood flow, potentially causing fetal hypoxia.-Phenylephrine may interact with oxytocic or ergot derivatives to cause persistent maternal hypertension; cerebral vessel rupture is possible.-Sympathomimetic amines are teratogenic in some animal models, but are not suspected to cause human teratogenicity.-First trimester exposure to phenylephrine may be linked to fetal abnormalities.-Patients with a preeclampsia history should use phenylephrine with caution due to its vasoconstrictive properties.-Phenylephrine may reduce placental perfusion. Use of imidazolines (found in nasal decongestant sprays and eye drops) was tied to an approximate doubling of risk for an abnormal connection between the trachea and esophagus. Phenylephrine: A monitoring study including 1249 mother-child pairs that had first trimester phenylephrine exposure showed an increase in malformation, with association greater with minor defects than major defects (8 eye and ear defects, 6 syndactyly, 4 preauricular skin tags, and 3 clubfoot cases); 4149 any time pregnancy exposures were associated with 15 congenital dislocation of the hip, 6 umbilical hernia, and 4 other musculoskeletal defects. Nasal decongestants can cause some general side effects, the most common of which is insomnia. Available for Android and iOS devices. If you take too much phenylephrine, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away. I know we can take Benedryl and the active ingredient is actually whats in Tylenol PM without the antecitaminophen. This medication may be prescribed for other uses. Learn more. are linked to rare birth defects of the digestive tract, ear and heart. Accidentally because I had a brain fart moment and forgot I was pregnant even though I know its not recommended during pregnancy So my rational brain is gone at the moment and Im freaking out that I could have harmed my baby. People can develop this condition in as little as 3 days of using a topical nasal decongestant. Higher doses of aspirin typically are not recommended during pregnancy. If phenylephrine is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. It is not known if phenylephrine crosses into human milk. Follow the directions on your prescription label carefully. I asked him about Nyquil to sleep cause any other time thats what I'd take with a cold to get a good nights rest. Common side effects of phenylephrine include nausea, vomiting, and headache. Insomnia is the most common side effect that people may experience when taking nasal decongestants. hypersensitivity (severe allergic reaction). This is called the background risk. Constriction of the blood vessels in the nose can provide short-term relief from nasal congestion. What are the best nasal decongestants by age? To pregnant mothers, ingested Sudafed PE may be detrimental to their health and the unborn baby compared to an inhalable form of Sudafed PE. Taking birth control pills during early pregnancy doesn't appear to increase the risk of birth defects. It is usually administered by a healthcare provider immediately prior to eye examinations or procedures. Phenylephrine can narrow the blood vessels in your uterus, which can decrease blood flow. Individuals can find phenylephrine in various over-the-counter medications for cold, flu, and allergy symptoms. The same applies to phenylephrine in Sudafed PE. Use these dosage charts for infants and children under 12 years old: The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Learn More Integer gravida Here's What You Need to Know, Surprising Side Effects of Sleeping Pills, Healthy Habits to Improve Your Eye Health. Eventually, that reduces the conditions to allow for normal breathing. Im 13 weeks. This drug should be used during pregnancy only if the benefit outweighs the risk to the fetus.AU TGA pregnancy category: B2US FDA pregnancy category: Not assigned Comments:-There is no data on use in pregnant women to know this drugs risks, including the risk of fetal harm or reproductive effects.-Acetaminophen is commonly used during pregnancy and has been assumed safe; recent data questions the safety, especially with routine use or varying genetics. Over-the-counter medicines DrugFacts. The symptoms that phenylephrine tends to deal with are nasal congestion and breathing. http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT" (2013). Every fetus depends on the same blood flow for every essential function to form ultimately. I would advise that whichever medication you take while pregnant be limited to only your doctors prescription. Immediate release: Take 60 mg every 46 hours, when needed. Medically reviewed by Drugs.com. WebIm 13 weeks. When such drugs interact with the phenylephrine in Sudafed PE, they may cause some profound adverse health effects, which may be detrimental to the lives and wellbeing of both mother and unborn fetus. Never use this subreddit as your first and final source of information regarding your question. We avoid using tertiary references. WebDoes taking phenylephrine increase the chance of birth defects? The shortness in blood flow may eventually result in defects during birth that may not be reversible and very regrettable. There are no controlled data in human pregnancy. [This story corrects the 7th paragraph of July 22 story by correcting stomach-defect risk increase to three-fold.]. Immediate release: Take 60 mg every 46 hours, when needed. They also reduce the risk of a fertilized egg implanting outside the uterus (ectopic pregnancy). By using our website, you consent to our use of cookies. Accessed July 15, 2022. Phenylephrine may be found in some form under the following brand names: Serious side effects have been reported with phenylephrine. Well, after taking the pill, I stupidly decide to do a search for each ingredient, and while all of the other ingredients were considered perfectly safe, there were not such good reviews for phenylephrine. Acetaminophen / phenylephrine is also known as: Alka-Seltzer Plus Cold and Sinus, Congespirin Aspirin Free, Contac Cold + Flu (Day Formula), D-Time Sinus, Day Relief Sinus PE, Dilotab II, Excedrin Sinus Headache, Mapap Sinus Congestion and Pain, Non-Pseudo Sinus Pain & Pressure, Robitussin Peak Cold Nasal Relief, Sinus Congestion and Pain Daytime Cool Ice, Sinutab Sinus Maximum Strength, Sudafed PE Sinus Pressure + Pain, Suphedrine PE Sinus Headache, Tylenol Plus Children's Cold & Stuffy Nose, Tylenol Sinus + Headache Day, Vicks QlearQuil Daytime Sinus & Congestion, Vicks Sinex Daytime. But know that there is little risk of birth defects. This may result in a temporary worsening of their congestion. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. She was laterrecognized for her contributions to research in the area of alcohol dependence. Nasal congestion occurs when blood vessels within the sinuses and nasal passages become swollen and inflamed. Some of them may require surgery, but not all are life-threatening.. Label: Sudafed PE congestion phenylephrine hydrochloride tablet [Fact sheet]. i was talking with my doc, and the REAL sudafed (the stuff behind the counter) is okay the sudafed stored on the shelves isn't but he didn't say why just cuz its over the counter doesn't mean its okay for us! New comments cannot be posted and votes cannot be cast. I did however, get the best night's sleep I have had in a month. Is it possible for me to take phenylephrine and pseudophedrine? (2020). PHYSICIANS SHOULD COMPLETELY FAMILIARIZE THEMSELVES WITH THE COMPLETE CONTENTS OF THIS LEAFLET BEFORE PRESCRIBING PHENYLEPHRINE HYDROCHLORIDE OPHTHALMIC SOLUTION. My doc and pharmacist said absolutely ZERO benedryl or any antihistamine. Mitchell believes theres enough evidence indicating a possible connection to birth defects that doctors should not be recommending that pregnant women take decongestants, but should evaluate each womans need for the drugs on a case-by-case basis. Please contact the moderators of this subreddit if you have any questions or concerns. Last updated on Aug 29, 2022. (2017). This level means some animal studies suggest fetal risk but no human studies At 33 weeks of pregnancy both medications are fine to take. This medication comes in solution form and is instilled directly into the eye. Animal studies are not available for the combination product. Which Medications Are Safe During Pregnancy? A woman who uses decongestant medications like pseudoephedrine while in the first trimester of pregnancy Take phenylephrine exactly as prescribed. Sudafed PE is a class of medicines containing phenylephrine, a drug used to treat signs of flu, common cold, sinusitis, and some allergies, especially to cold and dusty environments. Top answers from doctors based on your search: Created for people with ongoing healthcare needs but benefits everyone. privacy practices. Enter multiple addresses on separate lines or separate them with commas. You could take some Benedryl to help you sleep too. Signs and symptoms of SS can vary but may include: A person taking MAOIs needs to stop taking them for 14 days before starting a decongestant. First-trimester use of phenylephrine, which is Mayo Clinic does not endorse companies or products. Interaction with other drugs. This is called the background risk. We will discuss several reasons why it may not be advisable for pregnant mothers to use Sudafed PE or any phenylephrine-containing drug. Normally, the first thing you'd do is reach for the nearest decongestant. http://www.tga.gov.au/docs/html/medpreg.htm" (2010): "Product Information. And phenylpropanolamine (Acutrim) was also linked to an eight-fold risk of defects of the ear and a three-fold increase in stomach defects. Phenylephrine falls into category C. No studies have been done in animals, and no well-controlled studies have been done in pregnant women. Phenylephrine is not considered safe for pregnant women, especially during the first trimester, because of its association with birth defects. Which Medications Are Safe While Breastfeeding? Is it safe to take cough remedies containing phenylephrine while pregnant? July 30, 2022. Spray Sudafed PE is believed to be safer than the ingested form since it does not affect either the uterus or the future wellbeing of the yet unborn baby. Since these drugs don't require a prescription and are routinely used without consulting a doctor, it's important to know what risks you may be putting your baby through. If you experience side effects, then stop using the drug, and see a How Climate Change Is Affecting Pregnancy. vomiting. Based Pregnancy categories A, B, C, D, and X are being phased out. Serious side effects have been reported with phenylephrine including the following: Phenylephrine can cause blurred vision. This medication is considered relatively safe in pregnancy (category c). Didn't find any significant interactions. Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, Antidepressant withdrawal: Everything you need to know. Phenylephrine can also cause blurred vision. i just called my doc on monday with another bad head cold and he said sudafed is on the safe list. However, if overdose is suspected, seek emergency medical attention. (2019). The lowest possible dose required to achieve the desired effect should be used. The fact that medications such as decongestants are typically and widely available for use without a prescription and do not require consultation with a healthcare provider should not be assumed to mean they are safe with respect to the fetus, since there are still relatively few studies that examine the risks and relative safety of these over-the-counter medications, which are more widely used in pregnancy than prescription medications, Mitchell said. The narrowing of blood vessels in pregnant women may happen in the uterus, adversely affecting the fetus and causing congenital disabilities. WebWhat will happen to my baby if i took a cough remedy containing phenylephrine while pregnant? Studies in animals are inadequate or may be lacking, but available data show no evidence of an increased occurrence of fetal damage.US FDA pregnancy category Not Assigned: The US FDA has amended the pregnancy labeling rule for prescription drug products to require labeling that includes a summary of risk, a discussion of the data supporting that summary, and relevant information to help health care providers make prescribing decisions and counsel women about the use of drugs during pregnancy. Dr. Allen Mitchell, the director of the Sloane Epidemiology Center at Boston University, conducted a study looking at babies born with birth defects from 1993 to 2010. Into category C. no studies have been done in animals, and allergy symptoms association! Cough remedy containing phenylephrine while pregnant that an overdose will occur topical nasal decongestant would advise whichever! Serious side effects have been done in pregnant women may happen in the area of alcohol dependence but everyone. 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Available for the nearest decongestant CONTENTS of this LEAFLET BEFORE PRESCRIBING phenylephrine HYDROCHLORIDE OPHTHALMIC.! And a three-fold increase in stomach defects monday with another bad head cold and he said Sudafed is on same. Some form under the following: phenylephrine can narrow the blood vessels to.... Can develop this condition in as little as 3 days of using topical. Healthcare provider or local Poison Control Center, or seek emergency medical attention right away following phenylephrine... And is instilled directly into the eye phenylephrine-containing drug whats in Tylenol PM without antecitaminophen...