They can give you tips on how to deal with any side effects that may be bothersome. Your doctor may do liver function tests before you start treatment and regularly during your Zetia treatment. Talk with your doctor right away if you have fever or chills with your joint pain. Zetia belongs to a class of drugs called cholesterol absorption inhibitors. Learn more about the link. (For more information on the specific conditions Zetia can treat, see the Zetia uses section.). The generic form of Zetia costs about the same as the generic form of Crestor. Brain fog. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, Homozygous familial hypercholesterolemia (HoFH), homozygous familial hypercholesterolemia (HoFH). Bock's fainting spells are one of the hallmarks of POTS. I am a stay at home mama to a sweet baby girl, and wife to an amazing h. The actual price youll pay for any of these drugs depends on your insurance plan, your location, and the pharmacy you use. * For these purposes, Zetia and Crestor are used to treat people of different ages. Zetia can also be used with statin drugs in adults. * For more information about this side effect, see " Zetia: Side effects explained " below. Lipitor is available in a generic form called atorvastatin. I read that Zetia should be taken along with a diet low in cholesterol and saturated fat. For most people, CoQ10 isnt a harmful or dangerous supplement. If youre concerned about weight gain while using Zetia, talk with your doctor. Tell them about all prescription, over-the-counter, and other drugs you take. Zetia reduces the buildup of fats, cholesterol, and other substances on the artery walls (this process is known as atherosclerosis) and if taken long term it may reduce the risk of heart disease. The autonomic nervous system controls systems like heart rate, blood pressure, digestion and temperature control, so people with dysautonomia may experience abnormal changes in blood pressure and heart rate, gastrointestinal issues, lightheadedness, fatigue, chest pain . People with this condition have high levels of plant sterols. (A class of drugs is a group of medications that work in a similar way.) Weight gain isnt a side effect reported in clinical studies of Zetia. Muscle-related problems are a possible side effect of Zetia when used with other medications. This is because it isnt safe to eat grapefruit or drink grapefruit juice while using a statin. Here we look at how Zetia and Crestor are alike and different. Examples of statin drugs include atorvastatin (Lipitor) and simvastatin (Zocor). Memory loss isnt a side effect of Zetia. However, skip your missed dose if its almost time for your next dose. Muscle problems are common side effects of statin drugs. A generic drug is an exact copy of the active drug in a brand-name medication. Clinical studies for ezetimibe did not note any difference in weight in those that took the drug versus those that did not. The generic is considered to be as safe and effective as the original drug. Talk with your doctor to learn more about which medications are right for you. Common sweetener erythritol tied to higher risk of stroke and heart attack, Gout: How metabolic syndrome may increase the risk, A new therapeutic target for the prevention of heart failure due to aortic stenosis, Skipping breakfast and fasting may compromise the immune system, Leqvio side effects: What you should know, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, 2.4% of people who took a statin drug alone, 2.5% of people who took Zetia with a statin drug, 2.2% of people who took a statin drug alone, 3.2% of adults and children who took Zetia with a statin drug experienced muscle pain, 2.7% of adults and children who took a statin drug alone experienced muscle pain, are taking other drugs that increase the risk of rhabdomyolysis, Chylomicrons, also known as ultra low-density lipoprotein or ULDL cholesterol. The manufacturer of Zetia hasnt given birth control recommendations for males using the drug. These include: Note: For more information about the potential negative effects of Zetia, see the Zetia side effects section above. Over an average of 8 to 12 weeks, people took either Zetia alone, Zetia with a statin drug, a statin drug alone, or a placebo. For primary high cholesterol, Zetia is FDA-approved for use in adults and children* to decrease levels of: For this purpose, Zetia is used with a low-cholesterol diet. They often originate at the base of the skull and spreading on the back of the head and neck. For instance, some interactions can interfere with how well a drug works. Within 4 to 12 hours of oral administration, a single 10-mg dose of Zetia reaches peak plasma concentrations of 3.4 to 5.5 ng/mL. Inability to speak. Its not known if Zetia is safe to take during pregnancy. As a result, it's critical to drink lots of fluid throughout the day to keep your hydration levels up. Your FAQs Answered: Life Expectancy and Familial Hypercholesterolemia, Inherited High Cholesterol and Heart Disease: What to Ask Your Doctor, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, Heart Disease: How ApoB Cholesterol Tests Can More Accurately Identify Risks, Treatments, The 5 Best At-Home Cholesterol Tests in 2023, African Americans, Cholesterol, and the Risk of Heart Disease, Heart Health Breakthroughs: Top Advancements and Innovations of 2022, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your mouth, tongue, or throat, which can make it hard to breathe, what dose of drug you were taking when you had the side effect, how soon after starting that dose you had the side effect, what your symptoms were from the side effect, what other medications you were also taking, any other information you feel is important, taking other medications, especially high dose statin drugs. Its not known if its safe to take Zetia while breastfeeding or if the drug passes into breast milk. For example, in studies, some people had to stop taking the drug because their liver enzyme levels increased. If you feel dizzy from Zetia, it may help to take your dose at bedtime. Crestor is available in a generic form called rosuvastatin. The most common side effects of Zetia include: muscle or joint pain, If you have joint pain while taking Zetia, you may also experience swelling, redness, or weakness in your joints. But its not clear whether this side effect occurred in studies. Using Zetia with medications in the fibrate drug class raises your risk of gallstones even more. Here's how ApoB tests can help doctors evaluate cholesterol levels and, in some cases, provide a better understanding of a, At-home testing can provide clarity about your cholesterol levels and risk of heart disease. To learn how Zetia and the other treatments in the study affected peoples levels of HDL (good) cholesterol, triglycerides, non-HDL cholesterol, and Apo B, see the prescribing information. Get medical help right away, if you have any of the symptoms listed above. Most of Zetias side effects should go away within a few days or weeks. joint or muscle pain*. It only comes in a strength of 10 milligrams (mg). Since every POTS patient is different, some may primarily experience gastrointestinal symptoms, such as nausea, vomiting or poor feeding, Berger explained. We avoid using tertiary references. Primary hyperlipidemia is a genetic condition caused by a mutation (change) in the genes that control how cholesterol is cleared from your body. POTS is a form of orthostatic intolerance that is associated with the presence of excessive tachycardia and many other symptoms upon standing. You can take Zetia at any time during the day, but try to take your dose around the same time each day. Medications in this drug class prevent your liver from making new cholesterol. More research is needed to know for sure. POTS was also linked, to a lesser degree, to Covid vaccination with an mRNA vaccine, according to the new study. Taking Zetia with a statin drug may increase your risk of developing some mild or serious side effects. In addition, you may need to watch out for grapefruit. This disorder affects the autonomic nervous system, which controls involuntary body functions such as body temperature and heart rate. Over time, plant sterols can build up in your blood vessels and raise your risk of heart disease. This is because every persons body responds differently to medications. Below are examples of these side effects. Zetia is indicated as an adjunct to a low-cholesterol diet for treatment of the following types of hyperlipidemia: For treatment of primary hyperlipidemia, Zetia is indicated to reduce total cholesterol, low-density lipoprotein (LDL) cholesterol, non-high-density lipoprotein (non-HDL) cholesterol, and apiloprotein B (ApoB). Zetia contains the active drug ezetimibe. In order to diagnose POTS, your doctor will need to measure your heart rate when you are sitting at rest. What are the serious side effects of Zetia? 22% in people who used Zetia with fenofibrate, 20% in people who used Zetia with fenofibrate, people who used Zetia with atorvastatin or simvastatin had their LDL levels reduced by an average of 21% to 27% (the percentage varied depending on the dosage used), people who used atorvastatin or simvastatin alone had their LDL levels reduced by an average of 7%, people who used Zetia had their sitosterol levels decreased by an average of 21% and their campstrol levels decreased by an average of 24%, people who used a placebo had their sitosterol levels decreased by an average of 4% and their campstrol levels decreased by an average of 3%, bile acid sequestrants, such as cholestyramine (Prevalite, Questran), colesevelam (Welchol), and colestipol (Colestid), statins, such as atorvastatin (Lipitor), rosuvastatin (Crestor), and simvastatin (Zocor), Both Zetia and Lipitor are FDA-approved to treat the following conditions* in adults when used with a. Zetia is also FDA-approved to treat the following conditions when used with a low-cholesterol diet: homozygous sitosterolemia in adults and in children ages 10 years and older. Your doctor may prescribe Zetia with a statin drug. Some people may develop mild or serious side effects during Zetia treatment. These lists contain up to 10 of the most common mild side effects that can occur with Zetia, with Crestor, or with both drugs (when taken individually). Yes, there are a few. The following lists contain some of the key side effects that may occur while taking Zetia. The actual price youll pay depends on your insurance plan, your location, and the pharmacy you use. Medications in this class prevent your small intestine from absorbing cholesterol. Tried Zetia again to rule out diet causing stomach issues but got same result. There arent any foods that have been specifically reported to interact with Zetia. (A drug class is a group of medications that work in a similar way.) Short term Zetia side effects include mild fatigue, dizziness, diarrhea, nausea and headache. POTS is commonly associated with low levels of fluid. The heart beats faster to pump it up to the brain, but with little success. If you have side effects of Zetia that bother you, talk with your doctor or pharmacist. Postural orthostatic tachycardia syndrome (POTS) is one of a group of disorders that have orthostatic intolerance (OI) as their primary symptom. We've provided a list of the best at-home tests for. It also isnt known what percentage of adults and children experienced diarrhea in clinical studies of other conditions treated with Zetia. You can use the study as a second opinion to make health care decisions. If you have multiple health conditions, your doctor may recommend other medications for you to take with Zetia. Zones: Annual Height/Spread: 3 to 4 feet tall, 2 to 3 feet wide Exposure: Full sun Bloom Time: Spring to frost Color: Golden yellow (shown), deep red, orange, carmine rose, coral, lime, wine, purple, bright pink, white, salmon rose, and scarlet. A Mayo Clinic study published this month in Pacing and Electrophysiology (PACE), suggests that a class of medications more commonly prescribed for older adults is a strong first-line treatment for teenagers with a debilitating condition called postural orthostatic tachycardia syndrome, or POTS. Lipitor contains the active drug atorvastatin. Porphyria patients are often overly sensitive to sunlight. This active drug is also available as a generic medication. So if youre taking Zetia with a statin drug, you may need to avoid eating grapefruit or drinking grapefruit juice during your treatment. Across studies, researchers looked at different groups of people to evaluate whether Zetia was safe and worked for their condition. POTS is an unusual condition in which your heart rate speeds up by 30 or more beats per minute with little or no change in blood pressure. Zetia isnt a statin drug. Physicians who treat dysautonomia can be located on our Physician List. It wasnt reported during studies of the drug. However, side effects are generally mild and go away as the body adjusts to the medication. The cause of the disorder is unknown. Zetia is a prescription drug used to treat certain types of high cholesterol. Also, Zetia use may cause increased liver enzyme levels, especially if its taken with a statin drug. Zetia is FDA-approved to lower your total cholesterol level, and triglycerides are one part of your total cholesterol level. You should also look for supplements from reputable manufacturers. Get answers to some frequently asked questions about Zetias side effects. The dosage is the same for all approved uses. upper respiratory tract infection, including the common cold. Postural orthostatic tachycardia syndrome (POTS) is a form of dysautonomia, or a malfunction of the autonomic nervous system. Tramadol will usually cause a blistering type rash with itching which you do not describe. For HoFH, Zetia is FDA-approved to decrease levels of total cholesterol and LDL cholesterol. Both Zetia and Crestor come as tablets that are swallowed. Ezetimibe (the active drug in Zetia) is also available in a combination drug that contains simvastatin. However, your cholesterol levels may increase if you stop taking the drug. Common side effects may include: diarrhea; cold symptoms such as stuffy nose, sneezing, sore throat; pain in an arm or leg; joint pain; or. Qu H, et al. Cholesterol can also be found in foods such as eggs, cheese, and meat. You may experience muscle problems as a side effect of Zetia. * Zetia is also approved to treat these conditions in children ages 10 years and older. In the video she posted on Thursday, the "Real Housewives of New York City" alum detailed her suffering from a severe dehydration issue and shared that her doctor . No, hair loss isnt a known side effect of Zetia. These lists contain examples of serious side effects that can occur with Lipitor or with both drugs (when taken individually). And your doctor can use this information to adjust your treatment plan if needed. Learn more about some of the side effects that Zetia may cause. Liver problems. For more information on possible side effects of Zetia, see the Zetia side effects section above. Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. Statins are drugs used to lower cholesterol. yellowing of your skin or the whites of your eyes, ahajournals.org/doi/10.1161/JAHA.118.009835, organon.com/product/usa/pi_circulars/z/zetia/zetia_pi.pdf, Alternatives to Statins for Lowering Cholesterol. Lipitor ( atorvastatin) and Zetia ( ezetimibe) are used to lower cholesterol levels in the blood. They can recommend treatments that may help with joint pain, or they may recommend a different treatment option for you. Call your doctor right away if you have serious side effects. You may also have muscle cramps, spasms, or stiffness. Examples of mild side effects that have been reported with Zetia include: * To learn more about this side effect, see the Side effects explained section below. This is especially helpful to do when you first start taking new drugs or using a combination of treatments. Zetia is sometimes used with medications in the statin drug class. See the Mild side effects and Serious side effects sections above for more information. Is the ketogenic diet right for autoimmune conditions? Talk with your doctor if you experience diarrhea while taking this medication. Bethenny Frankel is opening up about her health issue, explaining to her Instagram followers about her battle with postural orthostatic tachycardia syndrome (POTS) after receiving comments about the change in her physical appearance. Note: Some of the drugs listed here are used off-label to treat these specific conditions. While there's no cure, several treatments and lifestyle changes can help manage the symptoms of POTS. The Benary's Giants have large, double blossoms, 4 to 6 inches across, available in a rainbow of . They are caused by deficiencies in enzymes involved in the synthesis of heme. They may have suggestions depending on your weight and health goals. Learn about the drugs dosages, forms, strengths, and more. After first three days stopped it for two days. You may also be having a reaction to all the medications mixed together. 1. Nearly two years passed before Bock received an official diagnosis: postural orthostatic tachycardia syndrome, or POTS. Can diet help improve depression symptoms? Risk factors for muscle-related problems. It can develop suddenly or gradually over time. If youve noticed memory problems while taking Zetia, talk with your doctor. Zetias side effects are usually mild, especially if youre taking Zetia alone. Specific statins that were studied included atorvastatin (Lipitor), simvastatin (Zocor), pravastatin (Pravachol), and lovastatin. Read More. Your doctor may have you stop your Zetia treatment if it isnt safe or effective for you. Dr. said Zetia was different and would not cause these side effects, so I agreed to try it. Zetia generally costs less than Lipitor. Nexlizet (bempedoic acid/ezetimibe) is a prescription tablet used to lower LDL (bad) cholesterol in certain people. The generic is considered to be as safe and effective as the original drug. For those who aren't familiar with POTS, it is an often-disabling neurological condition that causes your heart rate to rise a great deal when you are upright, and often blood pressure drops when you are upright (when it should be rising), and it causes fainting, fatigue, headache, nausea, face and hand tingling, and blood pooling in legs. Brand-name medications usually cost more than generics. Zetias mechanism of action is considered complementary to that of statins and fenofibrate. . Zetia contains the active drug ezetimibe. You should always consult your doctor or another healthcare professional before taking any medication. In studies, some people had to stop taking Zetia because of this side effect. You can use the study as a second opinion to make health care decisions. 4. (A class of medications is a group of drugs that work in a similar way.) Would a lower dose of Zetia help to reduce my risk of side effects? Off-label use is when a drug thats approved to treat one condition is used to treat a different condition. When you get Zetia from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. (Mixed hyperlipidemia is also known as mixed high cholesterol.). And generics tend to cost less than brand-name drugs. Learn more about how grapefruit may interact with medications. In certain conditions (such as when traveling), you may temporarily store Zetia at temperatures of 59F to 86F (15C to 30C). Tell your doctor if youre experiencing bothersome side effects from Zetia. MS: Can the Mediterranean diet help preserve cognitive health? Watch Part 2 here: https://youtu.be/HPfo2QOa89YHello Friends! Zetia is approved to treat certain forms of high cholesterol in adults when used with a low-cholesterol diet. Our website services, content, and products are for informational purposes only. Zetia is a lipid-lowering compound used to treat high cholesterol.Common side effects of ezetimibe include diarrhea, abdominal pain, back pain, joint pain, muscle aches, and sinus infection ().. Serious side effects of ezetimibe include hypersensitivity reactions (including angioedema - swelling of the skin and underlying tissues of the head and neck - that can be life-threatening), skin rash . Zetia shouldnt cause weight gain or weight loss. For more information on these side effects, see Side effect details below. Effects of coenzyme Q10 on statin-induced myopathy: An updated meta-analysis of randomized controlled trials. Absorption isnt affected by food. Zetia may cause serious side effects including: muscle pain, muscle tenderness or weakness, fever, unusual tiredness, and. You may find your symptoms are worse in the morning, and they may change from day to day. However, animal studies dont always predict what will happen in humans. Zetia is FDA-approved to treat certain forms of high cholesterol in adults and children. Or they may recommend that you stop taking the medication. If you have questions about using Zetia and cholestyramine together, talk with your doctor. They may be able to suggest ways to relieve this side effect. Call 911 or your local emergency number if your symptoms feel life threatening or if you think youre having a medical emergency. Clinical studies involved adults and children ages 10 years and older. You may not have any symptoms of gallstones unless they cause your gallbladder to swell. What causes POTS? What Are the Injectable Alternatives to Statins? For more information about Zetia, including details about its uses, see this in-depth article on the drug. If your muscle-related side effects dont go away or become severe, tell your doctor right away. This may increase your risk of side effects. There arent any herbs or supplements that have been specifically reported to interact with Zetia. If your liver function tests show increased liver enzymes called transaminases while youre using Zetia with a statin drug, your doctor may stop your treatment. Or should I wait to see if I develop such side effects? This includes grapefruit and grapefruit juice. Bethenny Frankel is opening up about her health issue, explaining to her Instagram followers about her battle with postural orthostatic tachycardia syndrome (POTS) after receiving comments about . However, its important that you dont stop taking Zetia without first talking with your doctor. Some people have mild symptoms, while for others it can have a big impact on their everyday lives. Statins shouldnt be used during pregnancy. Taking Zetia with cholestyramine can decrease the amount of Zetia in your body. The phase IV clinical study analyzes which people take Zetia and have Diarrhea. However, your doctor will check your cholesterol levels about 4 weeks after you start treatment. Your risk of developing serious side effects may increase if you take Zetia with other medications to treat high cholesterol, such as statin drugs. Postural orthostatic tachycardia syndrome (POTS) is a condition characterized by lightheadedness or dizziness when standing and a racing heart. Below are medications that can interact with Zetia. stuffy nose. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. These drugs havent been directly compared in clinical studies. But it may be a sign that your liver isnt working as well as it should. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. However, you may still experience muscle problems if you use Zetia alone. This helps prevent others, including children and pets, from taking the drug by accident. A clinical study looked at children ages 10 to 17 years old with heterozygous familial hypercholesterolemia (HeFH). And taking it with Zetia and a statin likely wont cause any problems. People with this condition have high levels of LDL (bad) cholesterol. In addition, if ezetimibe is taken with a statin or fenofibrate, there may be an increased risk of . It is created by eHealthMe based on reports of 45,364 people who have side effects when taking Zetia from the FDA, and is updated regularly. Talk with your doctor if youre concerned about your risk of memory loss while using Zetia alone or with a statin drug. Homozygous sitosterolemia is a genetic condition caused by a mutation (change) in the genes that control how plant sterols are cleared from your body. As with all medications, the cost of Zetia can vary. Zetia may be used with statin drugs or with fenofibrate when used to treat certain conditions. This lack of blood to the brain and other organs can cause a variety of symptoms, including: Fainting. Some drugs used to lower cholesterol can also decrease the risk of poor health and the risk of death associated with heart disease. Get emergency medical help if you have signs of an allergic reaction to Zetia: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Repatha is a prescription drug prescribed to lower LDL cholesterol and certain cardiovascular risks. In Zetia's clinical studies, these were some of the side effects that occurred more often: pain in the arms or legs. Its also unknown how many adults and children experienced muscle weakness or muscle breakdown in these studies. Zetia isnt known to interact with grapefruit or any other foods. Causes of postural tachycardia syndrome (PoTS) It's not clear what causes postural tachycardia syndrome (PoTS). 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