Its just baffling. Although not all of these side effects may occur, if they do occur they may need medical attention. I cried. It was so helpful to me. I tried 1/2 every 2 days but last night I gave in and took a whole Zyrtec. If I take my last dose Monday morning at 8 AM Ill start sneezing uncontrollably by 8 PM on Tuesday. And for about a week, the hives didnt return. This severe itch lasted until day 7, when my itch scale was a 7 out of 10. I was able to get an urgent appointment with the allergy doc and he immediately recognized my symptoms as Zyrtec withdrawal. Let us know in the comments! It has been terrible! The hives are the worst. Thats when I knew what was happening. During these horrible seven days, I felt like insects were crawling all over my skin. Thanks for sharing your experience and helping me confirm its real and Im not crazy! She asked how long had I been off the zyrtec. I still itch a little every night (I wonder if I have a histamine intolerance) and I do fine with an Allegra or Benadryl. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Id itch a lot in the morning, then have a decent afternoon with only slight discomfort, and at night the the itch would intensify. A. I slept really well but in the morning felt horrible. Same with pepperminty shampoo and oils. And its frustrating thinking that you are alone. Use these dosage charts for infants and children under 12 years old: prednisone, fluticasone nasal, montelukast, loratadine, cetirizine, promethazine, Benadryl, diphenhydramine, Xolair. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. I am proud of myself. Still holding on taking the antibiotic. -Some experts recommend: Patients over 65 years of age should start with 5 mg orally once a day. It was titled: Intense pruritus or itching emerging after discontinuation of cetirizine has been the subject of postmarketing reports submitted to the U.S. Food and Drug Administration (FDA), published in the medical literature, and discussed on the internet. I only have these dreams as the latter.. If you experienced Zyrtec withdrawal we would like to hear from you. First generation H1 antihistamines cause drownsiness but should not cause withdrawal symptoms. Can I take Allegra in the morning and Zyrtec in the evening? Im kind of a PITA about taking meds, especially one that kills your immune system during flu season, so I opted to only use the topical. I make a small commission for purchases made through these links but it doesnt affect you or your pricing. Newer antihistamines, called selective H1-receptor antagonists, do not cross into the brain and have fewer side effects. Apparently it takes as many as 6 weeks after being cured for your body to work through the remaining allergens left by the mites under your skin. My symptoms are a runny nose/marathon sneezing, itchy eyes (only if I rubbed them after petting a cat) and a sore throat. Nights were the worst. We contacted the FDA about this discontinuation syndrome. Initially, there seemed to be skepticism, but eventually the agency published research confirming this reaction (Therapeutic Advances in Drug Safety, July 5, 2019). I have tried numerous times to rid myself of that medication as I highly suspect that all of the histamine blockers are the culprit for my constant weight gain over the past 5 years or so (naturally, Ive completed thorough testing to ensure nothing else could be the reason). I hadnt heard of Allegra or Claritin causing the same degree of withdrawal problems that Zyrtec does. Its not just Zyrtec. You are most definitely not crazy. I know for some people the heat made things worse, but I find that if I bring the area to the point of pain without burning it provides a couple hours of relief. #was, I have an amazing, supportive, crazy, adventurous, Simple beauty on the beach. The antihistamine withdrawal timeline depends on the specific drug. As a result of this review, the prescription levocetirizine Prescribing Information was revised to include the following information about pruritus after discontinuation of cetirizine in the Adverse Reactions-Postmarketing Experience section (6.2): FDA plans on publishing the results of the review in a peer-reviewed journal to further disseminate the information. We now believe it is a Zyrtec withdrawal reaction. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Apparently, histamine levels peak in the middle of the night (1-3 am) for most people, which would explain why I dreaded nights and felt uncomfortable in my own skin. My determination to conquer Zyrtec withdrawal was dwindling. For about a week scalp, eyes, arms were itching a lot and all in all it took 2 weeks. You can get through this! Overdose symptoms may include extreme drowsiness, vision problems, agitation, feeling restless and then drowsy or tired, fast heartbeats, stomach pain, nausea, vomiting, trouble walking, or trouble swallowing or speaking. I have often wondered if Zyrtec addiction was possible, but the relief I felt after taking it always outweighed anything else when it comes to my chronic urticaria and 100s of allergies. What a relief! Im incredibly thankful that I found this page. #nofilter #nofilterneeded What a drug! I then took Claritin for 3 days. Thanks for sharing! Im glad you found remedies to help with the itch. I may get drowsy but I just deal with it. I dont understand either why there are no warnings on these drugs. We comply with the HONcode standard for trustworthy health information. After the hives came back, my brain said take an allergy med and the hives went away. Right now I am itching like crazy; today I am calling my doc to see if she will give me anything for it. Thats exactly how it feels like bugs crawling on your skin. I have been taking Cetirizine (Zyrtec) for at least 10 years now. I am going through similar withdrawal symptoms, but its not from Zyrtec its from claritin. It is also used to relieve itching and hives. Upon starting my second week of withdrawal, the itching was still pretty constant, but the intensity had lowered. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. I did it as I would most other long-term drugs: I tapered it back. For me, exercise was my only escape. It works . And before or after any particular meal? Withdrawal from Zyrtec was one of the hardest things I ever had to do. Hi I do get cough and slightly weezy a bit. In 2007, the FDA approved Zyrtec, or cetirizine, as an over-the-counter drug to treat allergic rhinitis and chronic urticaria, a skin condition characterized by recurrent hives 2. Medical Disclaimer: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. We still could find nothing in the prescribing information or on the OTC label about Zyrtec withdrawal either. So glad for you Barbara! But every time I did, 24 hours from the last pill, like clockwork, I experienced horrible itching all over. Im hoping that it wont last long, and I will be able to see if the Zyrtec has contributed to the unexplained weight gain! Histamine is a substance produced by the body in response to allergic reactions that triggers immune response symptoms such as watery eyes, runny nose, and sneezing. Thanks for commenting. Read, Varicose veins arent just unsightly they can be detrimental to your health. And then I started still breaking out on one a day. Other second-generation antihistamines include fexofenadine (Allegra) and loratadine (Claritin). I couldnt understand what was happening, as I have never had allergy problems. palpitations, dry mouth, headache, fatigue, nausea, stomach pain, constipation, loss of appetite, stomach upset, nervousness, sleep problems (insomnia), sore throat, blurred vision, flushing (warmth, redness, or tingly feeling under your skin), restlessness or excitability (especially in children), skin rash or itching, Given the widespread availability of such products it would seem prudent for the FDA to investigate this withdrawal reaction and offer health professionals and consumers some information about 1) the possibility and 2) how to discontinue the drugs safely.. I noticed that within an hour or so of taking it that I would feel intense pressure in that ear and the whole area would become a hard knot. After two years of taking the allergy drug daily, Peter decided he wanted to stop, only to realize how dependent he had become on it. I just pushed through and tried not to think about it. Some nights Id use an ice pack on my hands or keep my hands in super cold water, which tamed the itch. As stated on the FDA website Potential Signals of Serious Risks/New Safety Information Identified from the FDA Adverse Events Reporting System FAERS, the potential safety issue of rebound pruritus [itching] with cetirizine, levocetirizine, and hydroxyzine was posted July September 2017, prompting evaluation to determine the need for regulatory action. I felt sorry for myself. Common nervous system side effects of Zyrtec include: drowsiness, dizziness, fatigue, and headaches. But I am scared as hell to become addicted to it too. But every time I missed taking it for some reason, I would end up way worse, with full-body hives. How long did it take? The itch was minimal (or gone!) Looking forward to the next 4 weeks for me! Thanks for letting us know what worked for you. Levocetirizine is an antihistamine used to relieve allergy symptoms such as watery eyes, runny nose, itching eyes /nose, and sneezing. I would love to never take another zyrtec but I dont think I can put myself through that agony again. Get emergency medical help if you have signs of an allergic reaction to Zyrtec: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Im in week 2 of the anxiety and it is terrible. Hopefully in a week itll be even less and this whole ordeal will be done and the mystery of the itch solved. If you take it long term you will experience the following : 1- weight gain 2- sleepiness 3-irritability 4-heart palpitations 5-svre anxiety 6-muscle twitches 7- hypertension 8-bloating 9- IBS Those are serious side effects. Fever. The withdrawal signs usually begin between 48 and 96 hours after the last dose. If I stayed away from alcohol, I didnt itch. Terry is one of the country's leading authorities on the science behind folk remedies. Just try to withdrawal when things are slower or easier with work or school and dont try this during busy months. It is considered a second-generation non-sedating antihistamine. Popped another Zyrtec and it went away. I grew up with a wide variety of animals and as an adult now work with them. It worked. Recreational marijuana is legal in Illinois and I have a medical marijuana license due to my degenerative disc disease. (Below are some Amazon affiliate links to products that helped me cope with Zyrtec withdrawal. Do not allow liquid medicine to freeze. Ive been zyrtec free for almost a week now and the itching is horrid. Here are just a few: Q. So itchy I just wanted to scratch my skin off, so itchy I was on the point of insanity. This needs to get researched! De Sutter A, Saraswat A, van Driel M. Antihistamines for the common cold. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. I was wondering if anyone else has this happen? The itch was a 3 out of 10, but still flared up to a 4-5 at night. Small commission for purchases made through these links but it doesnt affect you your... Myself through that agony again antihistamines cause drownsiness but should not cause withdrawal symptoms but. 7, when my itch scale was a 3 out of 10, but its not from was! Ask your doctor before using opioid medication, a muscle relaxer, medicine... Allergy med and the itching was still pretty constant, but still up. 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